Rare Disease Genetics
Miriam Schmidts
Fatty acid oxidation disorders: risk stratification, disease modifiers and metabolic networks
Ute Spiekerkötter
MetaboCF
MetaboCF
Human T cell Immunodeficiencies
Stephan Ehl
Epigenetic Regulation of Stem cells and Cancer
Manching Ku
Metabolism and Cofactor Enzymology
Luciana Hannibal
Hilda Biobank Freiburg
Hilda Biobank
Understanding Vascular Anomalies
Friedrich Kapp
Neuromuscular Diseases in Children and Adolescents
Astrid Pechmann
Clinical Trials and Registries
Study Office
Hematopoiesis and Leukemogenesis
Miriam Erlacher
Pediatric Endocrinology
Karl Otfried Schwab
EPIdiagnosis and EPItherapy of juvenile myelomonocytic leukemia
Christian Flotho
Adaptive Immunity
Oktay Kirak
Inborn errors of metabolism with a renal phenotype
Anke Schumann
Improving treatment in glycogen storage diseases and fatty acid oxidation defects
Sarah Grünert
Hematopoietic Stem Cell Transplantation in Primary Immunodeficiencies
Carsten Speckmann
Inherited and acquired disorders of primary and secondary hemostasis
Barbara Zieger
Pediatric epilepsy
Kerstin Alexandra Klotz and Julia Jacobs
Mitochondrial fatty acid oxidation and fatty acid biosynthesis
Sara Tucci
Cellular Innate Immunity
Philipp Henneke
Pediatric Healthcare Research
Thorsten Langer
Systems Biology of Lymphocyte Behavioral Regulation
Jan Rohr
Pediatric Sarcomas
Simone Hettmer
Rare Blood Disorders and Hematopoietic Stem Cell Transplantation
Brigitte Strahm
Research is central to the work of the Freiburg Center for Pediatrics and Adolescent Medicine. Our research strengths represent a wide spectrum of pediatric research. Our basic and translational research stimulates new understandings of disease mechanisms and inspires new approaches to treatment. Through our clinical research we test novel therapies which have been specifically adapted or newly developed to suit the needs of children and young people. And our healthcare research drives improvements that enable delivery of better care for children and their families in a complex and changing environment.
On the Research pages of this site, our leading researchers showcase their work. For more information about the Freiburg Center for Pediatrics and Adolescent Medicine, please visit our pages on the website of the Freiburg University Medical Center.
About the Freiburg Center for Pediatrics and Adolescent Medicine
Over €4.5 million
In 2018, the Freiburg Center for Pediatrics and Adolescent Medicine received over €4.5 million in external funding and grants.
Four Collaborative Research Centers
The Freiburg Center for Pediatrics and Adolescent Medicine coordinates one and participates in three further DFG-funded Collaborative Research Centers (SFBs):
- SFB 1160 "IMPATH: Immune-mediated pathology as a consequence of impaired immune reactions" (Speaker: Stephan Ehl, Pediatric Immunology)
- SFB 992 "Medical Epigenetics"
- SFB 1140 "KIDGEM: Kidney Disease – from genes to mechanisms"
- SFB/TRR167 "NeuroMac: Development, function and potential of myeloid cells in the central nervous system"
Six European Reference Networks
In association with the Freiburg Center for Rare Diseases, we are involved in six of the European Reference Networks for Rare Diseases:
- ERN-BOND for rare bone diseases
- EURO-NMD for rare neuromuscular diseases
- MetabERN for rare hereditary metabolic disorders
- PaedCan-ERN for pediatric cancer/hemato-oncology
- ERN-RITA for rare immunodeficiency, autoinflammatory and autoimmune diseases
- VASCERN for rare multisystemic vascular diseases.
200 publications
In 2018, our researchers were authors on almost 200 scientific publications.
120 clinical trials & registry studies
In 2018, the Freiburg Center for Pediatrics and Adolescent Medicine enrolled participants in over 120 clinical trials and register studies via our Study Office.
Research centers & networks
Researchers from the Freiburg Center for Pediatrics and Adolescent Medicine play a key role in many regional, national and international research centers and graduate colleges, including:
- the German Cancer Research Center (DKTK) and the Comprehensive Cancer Center Freiburg (CCCF)
- the Center for Chronic Immunodeficiency (CCI)
- the PRIMAL Consortium ("Priming Immunity at the Beginning of Life")
- the iMACnet project ("Genetically corrected iPSC-derived macrophages (i-MAC) for innovative gene therapeutic strategies")
- the Spemann Graduate School of Biology and Medicine
Recent News
New review: SARS-CoV-2 in children (Henneke group)
A systematic review of intra-household and close-contact SARS-CoV-2 transmission in children has just been published by members of Philipp Henneke's research group (led by Roland Elling). The paper was published in Frontiers [...]
Postdoc position at the Metabolomics Core Facility (metabolomics and bioinformatics)
The Translational Metabolomics Core Facility at the University Children’s Hospital, University Medical Center Freiburg, is looking for a Postdoctoral Researcher specializing in Metabolomics. The position is advertised here (deadline: 28 February 2021); [...]
New publication: SARS-CoV-2 in children (Henneke group)
The results of Part 1 of an ongoing study investigating the role of children and families in the spread of the novel coronavirus (SARS-CoV-2) have recently been published. The paper (in JAMA [...]