Fatty acid oxidation disorders: risk stratification, disease modifiers and metabolic networks
Ute Spiekerkötter
Pediatric epilepsy
Kerstin Alexandra Klotz and Julia Jacobs
Hematopoiesis and Leukemogenesis
Miriam Erlacher
MetaboCF
MetaboCF
Rare Blood Disorders and Hematopoietic Stem Cell Transplantation
Brigitte Strahm
Environmental Pathogens in Extreme Prematurity
Daniel Klotz
Oncogenic Signaling and Epigenetics in Hematological Malignancies
Senthilkumar Ramamoorthy
Inherited and acquired disorders of primary and secondary hemostasis
Barbara Zieger
Improving Intensive Care Outcomes
Hans Fuchs
Hematopoietic Stem Cell Transplantation in Primary Immunodeficiencies
Carsten Speckmann
Cellular Innate Immunity
Philipp Henneke
Clinical Trials and Registries
Study Office
Pediatric Healthcare Research
Thorsten Langer
Pediatric Endocrinology
Karl Otfried Schwab
Improving treatment in glycogen storage diseases and fatty acid oxidation defects
Sarah Grünert
Hilda Biobank Freiburg
Hilda Biobank
Inborn errors of metabolism with a renal phenotype
Anke Schumann
CRC/TRR 359 Perinatal Development of Immune Cell Topology (PILOT)
Philipp Henneke
Understanding Vascular Anomalies
Friedrich Kapp
Metabolism and Cofactor Enzymology
Luciana Hannibal
Pediatric Sarcomas
Simone Hettmer
EPIdiagnosis and EPItherapy of juvenile myelomonocytic leukemia
Christian Flotho
Neuromuscular Diseases in Children and Adolescents
Astrid Pechmann
Rare Disease Genetics
Miriam Schmidts
Human T cell Immunodeficiencies
Stephan Ehl
Research is central to the work of the Freiburg Center for Pediatrics and Adolescent Medicine. Our research strengths represent a wide spectrum of pediatric research. Our basic and translational research stimulates new understandings of disease mechanisms and inspires new approaches to treatment. Through our clinical research we test novel therapies which have been specifically adapted or newly developed to suit the needs of children and young people. And our healthcare research drives improvements that enable delivery of better care for children and their families in a complex and changing environment.
On the Research pages of this site, our leading researchers showcase their work. For more information about the Freiburg Center for Pediatrics and Adolescent Medicine, please visit our pages on the website of the Freiburg University Medical Center.
About the Freiburg Center for Pediatrics and Adolescent Medicine
Over €4.5 million
In 2018, the Freiburg Center for Pediatrics and Adolescent Medicine received over €4.5 million in external funding and grants.
Five Collaborative Research Centers
The Freiburg Center for Pediatrics and Adolescent Medicine coordinates two and participates in three further DFG-funded Collaborative Research Centers (SFBs or Transregios):
- SFB 1160 "IMPATH: Immune-mediated pathology as a consequence of impaired immune reactions" (Speaker: Stephan Ehl, Pediatric Immunology)
- SFB 992 "Medical Epigenetics"
- SFB 1140 "KIDGEM: Kidney Disease – from genes to mechanisms"
- SFB/TRR167 "NeuroMac: Development, function and potential of myeloid cells in the central nervous system"
- SFB/TRR359 "PILOT: Perinatal Development of Immune Cell Topology"(Speaker: Philipp Henneke, Pediatric Infectious Diseases)
Six European Reference Networks
In association with the Freiburg Center for Rare Diseases, we are involved in six of the European Reference Networks for Rare Diseases:
- ERN-BOND for rare bone diseases
- EURO-NMD for rare neuromuscular diseases
- MetabERN for rare hereditary metabolic disorders
- PaedCan-ERN for pediatric cancer/hemato-oncology
- ERN-RITA for rare immunodeficiency, autoinflammatory and autoimmune diseases
- VASCERN for rare multisystemic vascular diseases.
200 publications
In 2020, our researchers were authors on over 200 scientific publications.
120 clinical trials & registry studies
In 2018, the Freiburg Center for Pediatrics and Adolescent Medicine enrolled participants in over 120 clinical trials and register studies via our Study Office.
Research centers & networks
Researchers from the Freiburg Center for Pediatrics and Adolescent Medicine play a key role in many regional, national and international research centers and graduate colleges, including:
- the German Cancer Research Center (DKTK) and the Comprehensive Cancer Center Freiburg (CCCF)
- the Center for Chronic Immunodeficiency (CCI)
- the PRIMAL Consortium ("Priming Immunity at the Beginning of Life")
- the iMACnet project ("Genetically corrected iPSC-derived macrophages (i-MAC) for innovative gene therapeutic strategies")
- the Spemann Graduate School of Biology and Medicine
Recent News
Fully-funded PhD positions in TRR 359 PILOT (Perinatal Development of Immune Cell Topology)
The TRR 359 Transregional Collaborative Research Center “Perinatal Development of Immune Cell Topology (PILOT)” is a consortium which brings together scientists from several research institutions across Germany to research the development of the immune system [...]
ZKJ Research Day 2022
Around 120 participants attended the 4th Freiburg Pediatric Research Day at the ETAGE Conference Center on 29 November 2022. The program included three sessions of talks, 35 posters, a keynote address from Prof. Dr. [...]
DFG funding for a new Collaborative Research Center (TRR 359 PILOT)
A new transregional Collaborative Research Center (TRR 359) on the topic of Perinatal Development of Immune Cell Topology ("PILOT"), led by Philipp Henneke, has been awarded funding from the German Research Foundation (DFG). PILOT [...]