MetaboCF

MetaboCF2024-04-17T10:29:40+02:00

Translational Metabolomics Platform

Head: Luciana Hannibal, PhD
Research Group Leader
Head of Translational Metabolomics Core Facility

E: metabolomics@uniklinik-freiburg.de
T: +49 761 270 43710
F: +49 761 270 45270

Medical Center – University of Freiburg
Center for Pediatrics
Mathildenstr. 1
79106 Freiburg
Germany

TEAM

The Translational Metabolomic Core Facility is a research initiative of the Research Laboratory of Metabolism at the Centre for Paediatrics and Adolescent Medicine (ZKJ), Faculty of Medicine, University of Freiburg.

MetaboCF is led by Dr. Luciana Hannibal, Research Group Leader at the ZKJ, and is registered with the DFG’s Portal for Research Infrastructure (RIsources).

Luciana Hannibal, Ph.D.  (Metabolism, small-molecule mass spectrometry, quality assurance)
Dr. Urs Berger (Biomarkers, small-molecule mass spectrometry)
Sandra Ehret, Technical Assistant (Sample preparation, Small-molecule mass spectrometry, Laboratory Organization)

RESEARCH THEMES

MetaboCF welcomes research projects from the Faculty of Medicine, University of Freiburg, other faculties of the University of Freiburg, and external collaborations and partnerships. You can view the User Agreement here (pdf, German).

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MetaboCF supports the following directions in metabolomics:

  • Targeted metabolomics (pathway-specific and multi-pathway)
  • Metabolite profile Panels
  • Product analysis in chemical and biochemical reactions
  • Metabolic labelling (isotopic tracing)
  • Disease-Focused Metabolomic Panels
  • Standardization of biomarkers
  • Bioinformatics

MetaboCF has access to the following instrumentation:

  • UPLC Nexera X2/QTRAP Sciex 6500+ (Sciex)
  • TSQ Vantage TripleQuad (Thermo Scientific, in collaboration with ProtCF)
  • GC-MS system (7890 GC system coupled to a 5975C mass spectrometer, Agilent)
  • HPLC Waters 2965a with DAD and fraction collector
  • Stopped-Flow with double mixer and dual UV-Vis/Fluorescence detection
  • Plate reader (UV-vis, fluorescence)

 

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